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Oncology sample study XYZ-ONC-01: time to event (ADTTE)

Source: R/data.R
adtte.Rd

Progression-free survival, overall survival and duration of response of the simulated study XYZ-ONC-01 (see adsl), in months; and a safety endpoint, the time to the first treatment-emergent skin and subcutaneous tissue disorder, in days. PFS: to progression or death, censored at the last tumour assessment; OS: to death, censored at the cut-off; DOR: from the first confirmed CR / PR; TTSKIN: the safety set, from the first dose, censored at the end of the treatment-emergent period (30 days after the last dose, death or the cut-off).

Usage

adtte

Format

adtte: a data frame, one row per subject and parameter, with the subject keys (as in adrs), the subgroups of a forest plot (AGEGR1, SEX, RACE, ECOGBL, REGION1, STRATA1) and

PARAMCD, PARAM, PARAMN

PFS, OS, DOR, TTSKIN

STARTDT, ADT, ADY

origin and event / censoring dates

AVAL, AVALU

time (MONTHS; DAYS for TTSKIN)

CNSR, EVNTDESC, CNSDTDSC

censor (1) or event (0) and why

Source

Simulated by data-raw/gen_onco.R in the package's source, seed 20261016; not real patient data.

See also

Other oncology sample data: adae, adex, adlb, adrs, adsl, adtr, advs

Examples

pfs <- adtte[adtte$PARAMCD == "PFS", ]
tapply(pfs$CNSR == 0, pfs$TRT01P, sum)
#>  Drug X Control 
#>      77      78